Rare and heterogeneous manifestations of leucocyte adhesion deficiency type 1: report of two cases with diagnostic dilemmas and novel ITGB2 mutation
Abstract Background Primary immunodeficiency disorders (PID) are rare disorders with heterogeneous manifestations, overlapping with other diseases such as autoimmunity, malignancy, and infections.This makes the diagnosis very challenging and delays management.Leucocyte adhesion defects (LAD) are a group of PIDs in which patients lack adhesion molec