RARE AND HETEROGENEOUS MANIFESTATIONS OF LEUCOCYTE ADHESION DEFICIENCY TYPE 1: REPORT OF TWO CASES WITH DIAGNOSTIC DILEMMAS AND NOVEL ITGB2 MUTATION

Rare and heterogeneous manifestations of leucocyte adhesion deficiency type 1: report of two cases with diagnostic dilemmas and novel ITGB2 mutation

Abstract Background Primary immunodeficiency disorders (PID) are rare disorders with heterogeneous manifestations, overlapping with other diseases such as autoimmunity, malignancy, and infections.This makes the diagnosis very challenging and delays management.Leucocyte adhesion defects (LAD) are a group of PIDs in which patients lack adhesion molec

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The cardiovascular aspect of COVID-19

The coronavirus disease-2019 (COVID-19), an infectious disease caused by Severe Acute Respiratory Syndrome Coronavirus 2(SARS-CoV-2), has hit the world ID Holders very hard by affecting millions of people across countries hence posing a major health threat on a global scale.This novel virus is thought to enter and cause infection in its host throug

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Approach-bias predicts development of cannabis problem severity in heavy cannabis users: results from a prospective FMRI study.

A potentially powerful predictor for the course of drug (ab)use is the approach-bias, that is, the pre-reflective tendency to approach rather than avoid drug-related stimuli.Here we investigated the neural underpinnings of cannabis approach and avoidance tendencies.By elucidating the predictive power of neural approach-bias activations for future c

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EFFECT OF FENBENZYL AND FENBENDAZOLE ON THE ANTIOXIDANT STATUS IN DOGS DURING EXPERIMENTAL INFECTION WITH CAUSATIVE AGENT OF TOXOCARIASIS

The article presents the results of studies of the effect of fenbenzyl and fenbendazole on the antioxidant status in dogs under the experimental infection with a causative agent of toxocariasis.Experiments were performed on 18 dogs, two and four months old.Three groups of six animals in each were formed: control and two experimental.Puppies in all

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